期刊
IEEE TRANSACTIONS ON MEDICAL IMAGING
卷 20, 期 11, 页码 1131-1139出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/42.963816
关键词
diffusion tensor magnetic resonance imaging; DTI; DT-MRI; image processing; registration; spatial transformation; warp
类别
资金
- NINDS NIH HHS [R01-NS33662] Funding Source: Medline
We address the problem of applying spatial transformations (or image warps) to diffusion tensor magnetic resonance images. The orientational information that these images contain must be handled appropriately when they are transformed spatially during image registration. We present solutions for global transformations of three-dimensional images up to 12-parameter affine complexity and indicate how our methods can be extended for higher order transformations. Several approaches are presented and tested using synthetic data. One method, the preservation of principal direction algorithm, which takes into account shearing, stretching and rigid rotation, is shown to be the most effective. Additional registration experiments are performed on human brain data obtained from a single subject, whose head was imaged in three different orientations within the scanner. All of our methods improve the consistency between registered and target images over naive warping algorithms.
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