期刊
JOURNAL OF IMMUNOLOGICAL METHODS
卷 257, 期 1-2, 页码 213-220出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0022-1759(01)00467-7
关键词
inflammation; leukocytes; chemokines; cytokines; cantharidin
A skin blister technique is described which allows the investigation of acute inflammation in humans in vivo. Filter paper discs are placed on the skin, impregnated with cantharidin and covered with impermeable film held by adhesive tape. The assembly is easily applied, unobtrusive, stable and may be worn during normal activities. The blister formed at 24 h contains approximately 5 X 10(5)-5 X 10(6) cells, predominantly neutrophils and macrophages. Inflammatory cytokines and chemotactic factors are detectable in the blister fluid. The technique is useful for characterizing the acute inflammatory response in health and disease. (C) 2001 Elsevier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据