期刊
HUMAN IMMUNOLOGY
卷 62, 期 11, 页码 1266-1276出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S0198-8859(01)00324-X
关键词
cytokine gene polymorphisms; predicting GvHD; in vitro human skin explant model
类别
This present review concentrates on the recent results investigating the role of certain cytokine gene polymorphisms, including tumor necrosis factor a, interferon gamma, interleukin-6 (IL-6), IL-10, and IL-1 receptor antagonist, in allogeneic stem cell transplantation. The review discusses their potential role in predicting outcome and the development of a genetic risk index for graft-versus-host disease in human leukocyte antigen matched sibling transplants. By the comparative use of an in vitro human skin explant model, initial results suggest that certain polymorphisms may be associated with more severe disease. (C) American Society for Histocompatibility and Immunogenetics, 2001. Published by Elsevier Science Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据