期刊
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
卷 34, 期 11, 页码 1453-1456出版社
ASSOC BRAS DIVULG CIENTIFICA
DOI: 10.1590/S0100-879X2001001100013
关键词
Ouratea sp; Aspergillus flavus; biflavonoids; aflatoxins
The biflavonoids 6,6 -bigenkwanin, amenthoflavone, 7,7 -dimethoxyagastisflavone and tetradimethoxybigenkwanin isolated from Ouratea species were tested for inhibitory activity on Aspergillus flavus cultures. Suspensions of Aspergillus flavus spores were inoculated into 50 rut of YES medium at different biflavonoid concentrations: 5 and 10 mug/ml for 6,6 -bigenkwanin, amenthoflavone and 7,7 -dimethoxyagastisflavone, and 5, 10, 15 and 20 mug/ml for tetradimethoxybigenkwanin. The four biflavonoids showed inhibitory activity on aflatoxin B1 and B2 production (P <0.001), but did not inhibit fungal growth at the concentration tested (P >0.05). These results show that biflavonoids can be used for the development of agents to control aflatoxin production.
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