期刊
FORENSIC SCIENCE INTERNATIONAL
卷 122, 期 2-3, 页码 124-129出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/S0379-0738(01)00480-7
关键词
red hair; melanocortin 1 receptor; minisequencing
We describe a minisequencing protocol for screening DNA samples for the presence of 12 mutations in the human melanocortin 1 receptor gene (MC1R), eight of which are associated with the red hair phenotype. A minisequencing profile which shows homozygosity for one of these mutations or the presence of two different mutations would strongly indicate that the sample donor is red haired. The absence of any red hair causing mutations would indicate that the sample donor does not have red hair. We report the frequencies of MC1R variants in the British red haired population. Crown Copyright (C) 2001 Published by Elsevier Science Ireland Ltd. All rights reserved.
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