期刊
JOURNAL OF HEART AND LUNG TRANSPLANTATION
卷 20, 期 11, 页码 1233-1236出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S1053-2498(01)00322-9
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We treated 4 patients with refractory International Society of Heart and Lung Transplantation Grades IIIA to IV cardiac allograft rejection with extracorporeal photopheresis. Following treatment on 2 consecutive days, 3 patients demonstrated complete histologic reversal of rejection. The remaining patient improved more gradually, but manifested complete cessation of rejection following three 2-day treatments. We conclude that photopheresis is a safe and effective modality for the treatment of severe refractory cardiac allograft rejection and that these results support the use of photopheresis in this clinical setting.
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