期刊
EUROPHYSICS LETTERS
卷 56, 期 4, 页码 603-609出版社
E D P SCIENCES
DOI: 10.1209/epl/i2001-00563-6
关键词
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We introduce a general framework to study the processivity of molecular motors moving along a polar lament and discuss the average time spent attached to the lament as a function of a tangentially applied load. Our study of specific models suggests that the attachment time of a motor decreases with increasing ATP concentration and that double-headed motors such as kinesins lose their processivity under forcing conditions while processive single-headed motors are less sensitive to tangential forcing.
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