期刊
CLEVELAND CLINIC JOURNAL OF MEDICINE
卷 68, 期 11, 页码 945-951出版社
CLEVELAND CLINIC
DOI: 10.3949/ccjm.68.11.945
关键词
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Alendronate and risedronate, the two oral bisphosphonates approved in the United States for preventing and treating osteoporosis, have never been compared in direct head-to-head trials, but they appear to have similar pharmacokinetics, drug interactions, adverse effect profiles, and efficacy. Alendronate, however, can be given as a once-weekly dose, whereas risedronate is not yet available in this dosage form. On the other hand, alendronate is not approved for preventing glucocorticoid-induced osteoporosis, whereas risedronate carries this indication.
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