Syntheses and activities as trehalase inhibitors of N-arylglycosylamines derived from fluorinated anilines

Twelve N-arylglycosylamines were prepared in a one-pot reaction by treatment of D-glucose, D-galactose, D-mannose or D-xylose with fluorinated anilines in the presence of small amount of hydrochloric acid. The inhibitory activity against porcine trehalase and the fungicidal activity of the title compounds toward Rhizoctonia solani have been tested. (C) 2001 Elsevier Science Ltd. All rights reserved.