期刊
AUTOPHAGY
卷 9, 期 2, 页码 258-259出版社
LANDES BIOSCIENCE
DOI: 10.4161/auto.22739
关键词
sphingolipid; ceramide; mitophagy; mitochondrial fission; lipid-protein interaction; ceramide synthase
类别
资金
- NIDCR NIH HHS [R01 DE016572] Funding Source: Medline
In a recent study, characterization of novel mechanisms that regulate lethal autophagy revealed that C-18-ceramide stress mediates LC3B-II-ceramide binding on mitochondrial membranes to target autophagosomes for mitophagy induction and tumor suppression.
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