期刊
JOURNAL OF HEART AND LUNG TRANSPLANTATION
卷 20, 期 11, 页码 1224-1227出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S1053-2498(01)00304-7
关键词
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资金
- NHLBI NIH HHS [5T32 HL-07022-22] Funding Source: Medline
Inhaled nitric oxide (INO) has been shown to improve oxygenation and decrease intrapulmonary shunt and pulmonary hypertension in various lung diseases. In this study we report a patient with end-stage idiopathic pulmonary fibrosis and pulmonary hypertension who received INO after coronary artery bypass surgery, with significant improvement in arterial oxygenation and pulmonary arterial pressure. Using a pulsing delivery system, the patient continued to receive outpatient INO for 30 months while waiting for lung transplantation. Exercise study and two-dimensional echocardiogram, after 3 months of inhaled NO, demonstrated continued benefits of INO for improvement of arterial oxygenation, pulmonary arterial pressure and exercise tolerance.
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