期刊
AIDS
卷 15, 期 16, 页码 2191-2193出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00002030-200111090-00017
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In a randomized, parallel arm, open-label study, the effect of switching from ritonavir to either nelfinavir or nelfinavir plus saquinavir as part of a triple antiretroviral regimen was investigated in 16 patients with undetectable HIV-1 loads. Patients continued to use the same nucleoside reverse transcriptase inhibitors as before the switch of protease inhibitor. The period of follow-up was 48 weeks. In all patients HIV-1 load remained undectable, whereas CD4 cell counts remained stable. Furthermore, lipid markers improved after the switch.
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