Synthesis of N-substituted 1,4-dihydroquinolines from the Baylis-Hillman acetates via the successive SN2′-SNAr isomerization strategy

1,4-Dihydroquinolines 4a-e were prepared from the reaction of the Baylis-Hillman acetates of ortho-halobenzaldehydes and benzylamine or cyclohexylamine via the successive S(N)2'-SNAr isomerization strategy. (C) 2001 Elsevier Science Ltd. All rights reserved.