Stereoselective synthesis of enamides by a Peterson reaction manifold

[GRAPHICS] Vinylsilanes are converted into enamides by a sequence comprising epoxidation, nucleophilic ring opening of the resulting epoxysilanes with NaN3, and reduction of the azide, followed by a one-pot N-acylation/Peterson elimination process. This method is distinguished by its wide applicability and stereoselective course.