期刊
BRITISH JOURNAL OF CANCER
卷 85, 期 11, 页码 1624-1626出版社
NATURE PUBLISHING GROUP
DOI: 10.1054/bjoc.2001.2155
关键词
testicular cancer; avascular necrosis; chemotherapy steroids
类别
To study the prevalence of avascular necrosis in patients receiving chemotherapy for testicular cancer we invited 103 consecutive patients treated by chemotherapy to attend for MRI scan of the hips. Four of 47 (9% (CI 2-20%)) patients scanned and 4/103 (3.8% (CI 1-10%)) of patients invited to participate in the study had evidence of avascular necrosis. As not all patients in the study had completed the at risk period this equates to a 3-year actuarial risk of 6.3% (95% confidence limits (CI) 2.4-16.1). These data suggest that avascular necrosis is an uncommon but significant complication of chemotherapy including steroids as anti-emetics. (C) 2001 Cancer Research Campaign.
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