期刊
SEMINARS IN IMMUNOLOGY
卷 13, 期 6, 页码 381-390出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1006/smim.2001.0335
关键词
phagocytosis; Salmonella; Shigella; Yersinia; inflammation
类别
Phagocytosis of bacterial pathogens is at the heart of the pathogenesis of injections. Pathogens have evolved a large array of strategies to escape the deleterious effect of phagocytosis by, professional phagocytes among which avoiding phagocytosis, killing the phagocytes or surviving inside them are the most 'popular' solutions. Bacterial pathogens are also using induction of phagocytic entry, into non-professional phagocytic cells, such as epithelial cells, as a strategy of survival and multiplication. We have taken enteroinvasive micro-organ isms such as Yerisinia, Shigella and Salmonella as a paradigm of the significance of phagocytosis/antiphagocytosis in the development of an infection and on the elicitation of the host response.
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