期刊
SEMINARS IN THROMBOSIS AND HEMOSTASIS
卷 27, 期 6, 页码 639-651出版社
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-2001-18868
关键词
cytokines; endotoxin; coagulation; fibrinolysis; protein C
Disseminated intravascular coagulation (DIC) can complicate a number of diseases. DIC in the setting of sepsis is considered to result from strong activation of the coagulation system and concurrent inhibition of fibrinolysis and other anticoagulant pathways. Cytokines have been implicated as important mediators in these hemostatic alterations. This article summarizes recent insights into which cytokines are likely to be involved in the procoagulant response to systemic infection.
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