期刊
FEBS LETTERS
卷 509, 期 3, 页码 345-349出版社
WILEY
DOI: 10.1016/S0014-5793(01)03178-7
关键词
succinyl-CoA : (R)-benzylsuccinate; CoA-transferase; formyl-CoA : oxalate CoA-transferase; (E)-cinnamoyl-CoA : (R)-phenyllactate CoA-transferase; butyrobetainyl-CoA : (R)-carnitine CoA-transferase; 2-methylacyl-CoA racemase; ternary complex mechanism
CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuceinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases. (C) 2001 Federation of European Biochemical Societies. Published by Else,vier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据