期刊
SCIENCE
卷 294, 期 5550, 页码 2323-2328出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1066803
关键词
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资金
- NIGMS NIH HHS [R15 GM61690-01] Funding Source: Medline
Agrobacterium tumefaciens is a plant pathogen capable of transferring a defined segment of DNA to a host plant, generating a gall tumor. Replacing the transferred tumor-inducing genes with exogenous DNA allows the introduction of any desired gene into the plant. Thus, A. tumefaciens has been critical for the development of modern plant genetics and agricultural biotechnology. Here we describe the genome of A. tumefaciens strain C58, which has an unusual structure consisting of one circular and one linear chromosome. We discuss genome architecture and evolution and additional genes potentially involved in virulence and metabolic parasitism of host plants.
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