期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 11, 期 24, 页码 3103-3106出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(01)00655-2
关键词
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Replacement of the large hydantoin-indole moiety from our previous work with a variety of smaller heterocyclic analogues gave rise to potent CCR5 antagonists having binding affinity comparable to the hydantoin analogues, The synthesis, SAR, and biological profiles of this class of antagonists are described. (C) 2001 Elsevier Science Ltd. All rights reserved.
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