期刊
AUSTRALIAN VETERINARY JOURNAL
卷 91, 期 12, 页码 534-537出版社
WILEY-BLACKWELL
DOI: 10.1111/avj.12125
关键词
ACTH stimulation test; corticosterone; cortisol; koalas; stress
资金
- University of Queensland
- Department of Environment and Resource Management, Queensland State Government
BackgroundStress can play a role in disease incidence in all species via immunosuppression and has been implicated as a contributing factor in significant infectious diseases of koalas. Faecal cortisol measurement may represent a non-invasive methodology for quantifying stress in koalas. MethodsWe used an ACTH (adrenocorticotropic hormone) stimulation test (10IU) to induce sustained secretion of cortisol, which was measured in serum samples from four koalas and subsequently it was attempted to locate a corresponding elevation in either cortisol or corticosterone measurements within the faeces. ResultsAlthough ACTH administration resulted in an elevation of serum cortisol for at least 4h post injection, it was not possible to identify a corresponding peak in corticosterone or cortisol concentrations in extracts from the faeces, consistent with the known gut transit time of the koala. ConclusionFaecal cortisol and corticosterone metabolites may not be reliable indices of acute changes in cortisol secretion in the koala and studies that attempt to use faecal cortisol as an index of stress will need to be interpreted with caution.
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