期刊
CURRENT OPINION IN IMMUNOLOGY
卷 14, 期 1, 页码 136-145出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0952-7915(01)00309-0
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Phagocytosis is an evolutionarily conserved process utilized by many cells to ingest microbial pathogens, and apoptotic and necrotic corpses. Recent investigation has revealed a fundamental requirement for two co-ordinated cellular processes - cytoskeletal alterations and membrane trafficking - in the phagocytic event. Some elements of this machinery are co-opted by certain pathogens to gain entry into host cells.
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