期刊
MAGNETIC RESONANCE IN MEDICINE
卷 47, 期 2, 页码 215-223出版社
WILEY
DOI: 10.1002/mrm.10074
关键词
MRI; diffusion; tensor; tracts; association; axonal
资金
- NCRR NIH HHS [RR15241] Funding Source: Medline
- NIA NIH HHS [AG016028] Funding Source: Medline
- NIBIB NIH HHS [P41 EB015909] Funding Source: Medline
- NICHD NIH HHS [HD24061, HD37931] Funding Source: Medline
- NIMH NIH HHS [MH52886] Funding Source: Medline
Diffusion-tensor fiber tracking was used to identify the cores of several long-association fibers, including the anterior (ATR) and posterior (PTR) thalamic radiations, and the uncinate (UNC), superior longitudinal (SLF), inferior longitudinal (ILF), and inferior fronto-occipital (IFO) fasciculi. Tracking results were compared to existing anatomical knowledge, and showed good qualitative agreement Guidelines were developed to reproducibly track these fibers in vivo. The interindividual variability of these reconstructions was assessed in a common spatial reference frame (Talairach space) using probabilistic mapping. As a first illustration of this technical capability, a reduction in brain connectivity in a patient with a childhood neurodegenerative disease (X-linked adrenoleukodystrophy) was demonstrated. Magn Reson Med 47: 215-223, 2002. (C) 2002 Wiley-Liss, Inc.
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