期刊
BIOMATERIALS
卷 23, 期 4, 页码 1139-1145出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0142-9612(01)00228-9
关键词
hemocompatibility; hemolysis; heparin; polyamide; amidoamine and block copolymer
Blood compatibility of polyamides has been improved by introducing amido-amine groups in polymer backbone. Polyamide block-copolymer are synthesized by reacting amine end-capped polyamides with N,N'-methylene-bisacrylamide. Polyamide block-copolymers, thus produced found to have the ability of absorbing heparin. Heparinized polyamide block-copolymers have shown significant improvement in blood compatibility as evident from thrombus formation and hemolysis studies. (C) 2001 Elsevier Science Ltd. All rights reserved.
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