期刊
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
卷 34, 期 2, 页码 213-217出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00005768-200202000-00005
关键词
beta(2)-agonist; exercise; ergogenic agent
Purpose: To determine the effect of formoterol (formoterol fumarate dihydrate) on the aerobic and anaerobic capacities of highly trained athletes. Methods: 10 male athletes (age = 26.2 +/- 0.9, (V) over dot O-2max = 65.6 +/- 2.4 mL(.)kg(-1.)min(-1)) with minimal bronchial reactivity to aerosols (i.e., negative methacholine challenge test) completed three identical exercise sessions differing only by the medication administered. Formoterol (F) a long-acting beta(2)-agonist, presently not approved for international competition by the I.O.C. Medical committee, was compared with salbutamol (S), an accepted bronchodilator, and a placebo (P). Formoterol (12 mug), salbutamol (400 mug), or placebo was administered by a Turbuhaler, 10 min before exercise testing in a double-blind, randomized, three-way crossover design. Testing sessions included a Wingate anaerobic test followed 15 min later by an incremental cycle ergometer test to exhaustion. Results: There were no significant differences between the groups in (V) over dot O-2max (F = 66.5 +/- 2.7; S = 67.8 +/- 2.5; P = 67.5 +/- 2.1 mL(.)kg(-1.)min(-1)) or Wingate peak power (F = 885 +/- 40; S = 877 +/- 40; P = 885 +/- 44 W) values. During the maximal aerobic test. no differences were observed in maximum minute ventilation, respiratory exchange ratio, heart rate, or work between the three experimental conditions. Also, there were no differences in the Wingate anaerobic test variables, total work, or fatigue index. Conclusion: Formoterol, administered in one aerosolized therapeutic dose, does not have an ergogenic effect in elite athletes without asthma.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据