期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 133, 期 2, 页码 153-155出版社
CONSULTANTS BUREAU
DOI: 10.1023/A:1015546821875
关键词
endotoxin; systemic endotoxemia; chronic viral hepatitis B and C; pathogenesis
Incidence and severity of systemic endotoxemia in patients with chronic viral hepatitis B and C were studied using the limulus test. Healthy subjects and patients with acute viral hepatitis B and C comprised reference groups. The incidence of physiological systemic endotoxemia in healthy subjects was 31.3%, while in chronic hepatitis systemic endotoxemia was found in 69-84% patients and it was more severe in this case. A significant correlation was revealed between systemic endotoxemia with virus replication and the degree of basic clinical and laboratory signs in patients with chronic viral hepatitis B.
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