A novel industrial-level reactor with two dynamic changes of air for solid-state fermentation

A novel industrial-level solid-state reactor (70 m(3)) with two dynamic changes of air was designed and has been put into operation successfully, in which the unite of virulence of Bacillus thuringiensis produced is maintained above 18,000 IU/mg. Two dynamic changes of air (including air pressure pulsation and internal circulation) in the fermentor can increase mass and heat transfers, as well as improve the porosity within the substrate. The reactor is novel and of significance in exploiting numerous socioeconomic advantages of solid-state fermentation.