Cerium(III) chloride promoted highly regioselective ring opening of epoxides and aziridines using NaN3 in acetonitrile:: A facile synthesis of 1,2-azidoalcohols and 1,2-azidoamines

[GRAPHICS] convenient and efficient synthesis of 1,2-azidoalcohols and 1,2-azidoamines has been achieved by ring opening of epoxides and aziridines using cerium(Ill) chloride and sodium azide in acetonitrile. The reaction is highly regloselective and afforded the corresponding products in good to excellent yields under mild and neutral reaction conditions. The method is very rapid and equally compatible for both epoxides and aziridines.