Enantioselective hydrogenation of isophorone with titania supported Pd catalysts modified by (-)-dihydroapovincaminic acid ethyl ester effect of the support and the reduction method

Enantioselective hydrogenation of isophorone was investigated over Pd/TiO2 catalysts in the presence of (-)-dihydroapovincaminic acid ethyl ester. The used supports were different in crystalline form and in surface area. The influence of the catalyst preparation method on the optical purity was studied. The catalysts were characterized by H-2 adsorption and SEM. (C) 2002 Elsevier Science B.V. All rights reserved.