期刊
NEUROSCIENCE LETTERS
卷 321, 期 3, 页码 141-144出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/S0304-3940(01)02470-3
关键词
serine protease; cultured hippocampal neuron; neurite outgrowth; aggregation; fasciculation
A serine protease neuropsin expressed in the hippocampus of adult brain has been implicated in synaptic plasticity. We report here that endogenous neuropsin was localized extracellularly in neuronal cell bodies and their neurites in mouse hippocampal cultures. Furthermore, we found that, in cultured mouse hippocampal neurons, recombinant neuropsin enhanced neurite projection from soma after 14 h of culture and neuronal aggregation with neurite fascicles at 48 h. This suggests that neuropsin is involved in neurite outgrowth and fasciculation during the development of the nervous system. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据