期刊
PHARMACEUTICAL BIOLOGY
卷 40, 期 2, 页码 117-128出版社
TAYLOR & FRANCIS LTD
DOI: 10.1076/phbi.40.2.117.5846
关键词
immunomodulating activity; complement fixation; polysaccharides; wound healing; traditional medicine; ethnobotanical survey; Mali
Identification of 123 species. belonging to 50 families, used for wound healing in the Bamako region of Mali, was performed in this study. The fifteen species that were most frequently cited by the traditional healers were subjected to chemical and biological studies. Water extracts were subjected to screening for effects on the human complement system in vitro. The monosaccharide composition and the total carbohydrate content of the extracts were also determined. All extracts showed effects on the complement system. but extracts from Biophytum petersianum Klotzsch., Pterocarpus erinaceus Poir, Podaxon aegyptiacus Mont.. Stereosperinum kunthianum Cham., and Ximenia americana L. had the highest activity. The content of carbohydrate in the extracts varied between 5% and 80% and most of them contained substantial amounts of the monosaccharides arabinose, rhamnose, galactose, glucose and galacturonic acid.
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