Modulation of insulin signaling in human skeletal muscle in response to exercise

KIRWAN, J.P., and M. JING. Modulation of insulin signaling in human skeletal muscle in response to exercise. Exerc. Sport Sci. Rev., Vol. 30, No. 2, pp. 85-90, 2002. Exercise is widely recommended for the treatment of obesity, insulin resistance, and type II diabetes mellitus. Recent discoveries in the molecular and cellular regulation of insulin-mediated glucose metabolism in skeletal muscle have provided a deeper understanding of how exercise modulates insulin action.