期刊
SEMINARS IN NUCLEAR MEDICINE
卷 32, 期 2, 页码 92-96出版社
W B SAUNDERS CO
DOI: 10.1053/snuc.2002.31564
关键词
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Several tumors overexpress somatostatin receptors (SSTR) and can thus be imaged with radiolabeled analogues of somatostatin. Tc-99m depreotide is a new radiolabeled somatostatin analogue that shows high affinity for SSTR2, SSTR3, and SSTR5 subtypes. It has been recently FDA-approved for use in the evaluation of indeterminate solitary pulmonary nodules. SPECT with Tc-99m depreotide is highly accurate in this clinical setting and may be preferable to FDG-PET because of its lower cost and wider availability. Large studies are also underway to evaluate the accuracy of Tc-99m depreotide in staging of lung cancer. Copyright 2002, Elsevier Science (USA). All rights reserved.
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