期刊
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
卷 51, 期 5, 页码 455-459出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1479-828X.2011.01343.x
关键词
assisted reproductive technology; diet; exercise; fertility; in vitro fertilisation; pregnancy; weight loss
资金
- NHMRC
- Brailsford Robertson Grant
- University of Adelaide in Adelaide, Australia
- Novartis USA
Obesity worsens and modest weight loss improves female fertility. Overweight women were randomised to lifestyle or standard treatment pre-in vitro fertilisation with treatment cessation at embryo transfer. There was a greater reduction in weight (P < 0.001) for lifestyle treatment (-3.8 +/- 3.0 kg, P < 0.001) compared with no changes for standard treatment (-0.5 +/- 1.2 kg, P = 0.092). Both the intervention (-5.3 +/- 4.6 cm) and control (-3.5 +/- 3.5 cm) group had reductions in waist circumference (P < 0.001) with no differences between the two groups (P = 0.215). The overall pregnancy rate was 53% (20/38) for the intervention and control group combined.
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