期刊
CURRENT OPINION IN IMMUNOLOGY
卷 14, 期 2, 页码 165-171出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0952-7915(02)00316-3
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NKT cells are key players in the regulation of antitumor immunity, particularly in experimental models of tumor immunotherapy, such as IL-12 or alpha-galactosylceramide administration. They may also operate in natural antitumor immunity. NKT cells are best known for their immunosuppressive functions; however, NKT cells interact with a range of other cell types (particularly dendritic cells and NK cells) and the outcome of NKT-cell stimulation depends on these and on the cytokine/co-stimulatory milieu.
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