期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 13, 期 2, 页码 161-166出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0958-1669(02)00303-8
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Various strategies have been developed to exploit plants as bioreactors for the production of pharmaceutical antibodies, to engineer antibody-mediated pathogen resistance or to alter the plant phenotype by immunomodulation. Recent research developments focus on the fine-tuning of expression systems and the detailed characterisation of recombinant products, including the implications of plant-specific glycosylation. Meanwhile, the first of these plant-derived antibody products has successfully completed early phase clinical trials.
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