期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 3, 期 4, 页码 246-255出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm780
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Proteins that are misfolded in the endoplasmic reticulum are transported back into the cytosol for destruction by the proteasome. This retro-translocation pathway has been co-opted by certain viruses, and by plant and bacterial toxins. The mechanism of retro-translocation is still mysterious, but several aspects of this process are now being unravelled.
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