期刊
BRAIN RESEARCH BULLETIN
卷 57, 期 6, 页码 833-838出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0361-9230(01)00774-2
关键词
regeneration; spinal cord injury; transplantation; neurotrophin
资金
- NIA NIH HHS [AG10435] Funding Source: Medline
- NINDS NIH HHS [NS37083] Funding Source: Medline
Several experimental strategies have been employed to minimize tissue damage and to enhance axonal growth and regeneration after spinal cord injury. The transplantation of suitable cell types to provide an axonal growth substrate and the application of growth factors have been shown to augment morphological and sometimes functional recovery. In this review we discuss the use of neural stem cell transplants and neurotrophic factor delivery by gene therapy to improve axonal regeneration in animal models of spinal cord injury. (C) 2002 Elsevier Science Inc.
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