期刊
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
卷 1574, 期 3, 页码 215-222出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0167-4781(01)00323-2
关键词
human; short chain dehydrogenase/reductase; gene; chromosome 14; gene expression
We have previously described the cloning of Hep27, a short-chain dehydrogenase/reductase, which is synthesized in human hepatoblastoma HepG2 cells following growth arrest induced by butyrate treatment. The present report describes the cloning, the structure and the physical and cytogenetic mapping of the gene coding for Hep27. We also show that Hep27 is synthesized in a limited number of human normal tissues and that it is localized in the nuclei and cytoplasm of HepG2 cells. (C) 2002 Elsevier Science B.V. All rights reserved.
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