期刊
JOURNAL OF CELL BIOLOGY
卷 157, 期 2, 页码 199-203出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.200201052
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- NIGMS NIH HHS [R01 GM047842, GM47842] Funding Source: Medline
Although the budding yeast centromere is extremely short (125 bp) compared to those of other eukaryotes, the kinetochore that assembles on this DNA displays a rich molecular complexity. Here, we describe recent advances in our understanding of kinetochore function in budding yeast and present a model describing the attachment that is formed between spindle microtubules and centromeric DNA. This analysis may provide general principles for kinetochore function and regulation.
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