期刊
AUSTRALASIAN JOURNAL OF DERMATOLOGY
卷 53, 期 1, 页码 70-72出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1440-0960.2011.00783.x
关键词
diabetes; dipeptidyl peptidase IV; psoriasis; sitagliptin
类别
Psoriatic patients have a higher prevalence of diabetes mellitus type 2 (DM). Since dipeptidyl peptidase IV (DPP-IV) dysregulation is present in DM and psoriasis, DPP-IV inhibitors have been proposed as therapeutic agents for both conditions. We report a psoriasiform eruption induced by sitagliptin, a DPP-IV inhibitor. The role of DPP-IV in the pathogenesis of DM is well established; however data on psoriatic patients is contradictory. More studies are required to elucidate the effect of DPP-IV inhibitors and their relationship with DM and psoriasis.
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