Fringe phenotypes in autism:: a review of clinical, biochemical and cognitive studies

Progress in identifying the genetic vulnerability factors in autism requires correct identification of the inherited phenotype(s). This can be achieved not only by the accurate description of the affected subject but also by the identification of vulnerability traits in non-affected relatives of autistic probands. This review will focus on this last strategy and principally on clinical, biochemical and cognitive traits. (C) 2002 Editions scientifiques et medicales Elsevier SAS.