期刊
NATURE NEUROSCIENCE
卷 5, 期 6, 页码 580-588出版社
NATURE AMERICA INC
DOI: 10.1038/nn862
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资金
- NIMH NIH HHS [F32 MH012145, F32 MH012145-01] Funding Source: Medline
A localized cluster of neurons in macaque posterior parietal cortex, termed the parietal reach region (PRR), is activated when a reach is planned to a visible or remembered target. To explore the role of PRR in sensorimotor transformations, we tested whether cells would be activated when a reach is planned to an as-yet unspecified goal. Over one-third of PRR cells increased their firing after an instruction to prepare a reach, but not after an instruction to prepare a saccade, when the target of the movement remained unknown. A partially overlapping population (two-thirds of cells) was activated when the monkey was informed of the target location but not the type of movement to be made. Thus a subset of PRR neurons separately code spatial and effector-specific information, consistent with a role in specifying potential motor responses to particular targets.
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