期刊
JOURNAL OF BACTERIOLOGY
卷 184, 期 11, 页码 3122-3125出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.184.11.3122-3125.2002
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Borrelia burgdorferi gene expression within the guts of engorging Ixodes scapularis ticks was examined by use of differential immunoscreening and differential expression with a customized amplified library. Fourteen chromosomal genes involved in energy metabolism, substrate transport, and signal transduction and 10 (4 chromosomal and 6 plasmid) genes encoding putative lipoproteins and periplasmic proteins were preferentially expressed in engorging ticks. These data demonstrate a new approach to the global analysis of B. burgdorferi genes that are preferentially expressed within the vector during feeding.
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