期刊
CANADIAN JOURNAL OF CHEMISTRY
卷 80, 期 6, 页码 646-652出版社
CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
DOI: 10.1139/V02-079
关键词
dihydropyrimidinone; enzymatic resolution; palladium coupling
The convergent synthesis of a potent alpha(1A)-selective adrenoceptor antagonist is described. Salient features of the synthesis include the enzymatic resolution of a racemic dihydropyrimidinone and the use of a palladium coupling reaction in the synthesis of 2,4'-dipyridyl.
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