期刊
JOURNAL OF GASTROENTEROLOGY
卷 37, 期 -, 页码 50-54出版社
SPRINGER-VERLAG TOKYO
DOI: 10.1007/BF02990100
关键词
apoptosis; hepatocellular carcinoma; hepatitis C virus; infalmmation; MAP kinase; NF kappa B
Hepatitis C virus (HCV) causes chronic hepatitis and is linked to the development of hepatocellular carcinoma (HCC). The role of HCV infection in the development of HCC remains to be clarified. We analyzed the effect of HCV core protein on modulation of cell proliferation. HCV core protein was shown to have at least two functions: activation of the Ras/Raf signaling pathway and anti-apototic function.
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