期刊
PSYCHIATRY AND CLINICAL NEUROSCIENCES
卷 56, 期 3, 页码 301-302出版社
WILEY
DOI: 10.1046/j.1440-1819.2002.00988.x
关键词
antidromic re-entrainment; eastward flight; jet lag; melatonin; natural zeitgeber; orthodromic re-entrainment
The effect of 3 mg of melatonin on the rate of re-entrainment of plasma melatonin rhythm after an 11-h eastward flight was assessed. Eight subjects participated in the study, and underwent 24-h blood samplings once before the flight and twice after the flight. Subjects were exposed to natural zeitgeber outdoors and took 3 mg of malatonin at 20:00 h local time on the days when no blood sampling was done. Antidromic re-entrainment was dominant whereby melatonin administration in the evening promoted re-entrainment. Melatonin accelerated the rate of re-entrainment by 15 min per day and alleviated the jet lag symptoms.
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