期刊
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
卷 42, 期 3, 页码 217-224出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S1040-8428(01)00217-7
关键词
antimony; bismuth; cancer
The main group elements antimony and bismuth are used clinically, primarily for the treatment of Leishmaniasis (antimony) and ulcers (bismuth). Despite their medicinal efficacy, the exploration of the anti-cancer potential of antimony and bismuth compounds is not as well developed as for other metal-containing species. The results of cytotoxicity and anti-tumour screening for antimony(III), antimony(V) and bismuth(III) compounds are summarised in this review. While this is a relatively undeveloped field of research endeavour, promising anti-tumour activity has been reported, in particular for bismuth compounds. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
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