期刊
NATURE
卷 417, 期 6890, 页码 763-767出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nature00815
关键词
-
资金
- NIGMS NIH HHS [R01 GM056265] Funding Source: Medline
Cryptochromes are blue/ultraviolet-A light receptors that mediate various light responses in plants and animals(1,2). But the initial photochemical reaction of cryptochrome is still unclear. For example, although most photoreceptors are known to undergo light-dependent protein modification such as phosphorylation (3,4), no blue-light dependent phosphorylation has been reported for a cryptochrome. Arabidopsis cryptochrome 2 (cry2) mediates light regulation of seedling development and photoperiodic flowering(5,6). The physiological activity and cellular level of cry2 protein are light-dependent(5-8), and protein-protein interactions are important for cry2 function(9,10). Here we report that cry2 undergoes a blue-light-dependent phosphorylation, and that cry2 phosphorylation is associated with its function and regulation. Our results suggest that, in the absence of light, cry2 remains unphosphorylated, inactive and stable; absorption of blue light induces the phosphorylation of cry2, triggering photomorphogenic responses and eventually degradation of the photoreceptor.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据