期刊
CELL CYCLE
卷 1, 期 4, 页码 253-255出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/cc.1.4.133
关键词
Anaphase; Securin; Sister chromatid; separation
类别
Mitotic progression requires the dissolution of cohesion between sister chromatids. Cohesion is dissolved by an essential protease known as separase. Separase is highly conserved throughout evolution and is subjected to multiple levels of regulation. Here we discuss recent studies that unravel several key mechanisms for regulating separase activity.
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